Webinar: EPA’s Four Lab Study

Wed. 5 May 2021 –

Join us for a conversation with Glenn Rice and his team on Wednesday, May 5, 2021, from 11:00am 12:00pm EST as they discuss Transdisciplinary Research Highlights and Challenges Encountered During EPA’s Four Lab Study of Risks Posed by Disinfection By-product Mixtures.

Rice is a SRA fellow and member of the EPA (United States Environmental Protection Agency). In this research, the four lab team conducted a study that examined reproductive and developmental effects in laboratory rats following treatment with a whole mixture of drinking water disinfection byproducts (DBPs). It was important to undertake this study because of the widespread exposures in the U.S. population and the reproductive and developmental health effects previously reported in some epidemiological studies of DBP mixtures and in some toxicological studies of individual DBPs.

A team of drinking water treatment engineers, toxicologists, chemists, and risk assessors collaboratively initiated, designed and conducted the study to produce results relevant to DBP health risk assessment.

A brief breakdown of the study and its researchers are provided here:

  • Glenn Rice: The Four Lab Study: Overview of a Multidisciplinary Challenge
  • Thomas Speth: Preparation of Concentrates: Challenges and Unique Solutions
  • Susan Richardson: Four Lab DBP Concentrates: Important Chemistry Considerations for Animal Exposures
  • Linda Teuschler: Analyses of Statistical Power of the Study and Stability of the Four Lab DBP Concentrates
  • Jane Ellen Simmons: Summary of Four Lab Study: Strengths of a Transdisciplinary Mixtures Study and Lessons Learned

Register Here